Jedi Mind Trick: You want to come to ASU.


I’d like to thank Douglas and everyone for their kind words about my “cloning experiment” and impending appointment to Arizona State in Tempe.

I will be part of the Center for Evolutionary Medicine and Informatics in the Biodesign Institute and the Evolutionary Biology Program in the School of Life Sciences. I was hired as part of a genomics cluster, which is currently still hiring (Initial deadline is this Friday. See the ad below.) You could have the office next to me and Prof. Steve Steve.

I am looking to take students and graduate recruitment is underway. I’m looking for students with a background in biology, computation, mathematics, and/or statistics and interested in studying evolution theory and bioinformatics. I work on a variety of topics in computational evolutionary genetics, with most of my research dealing with mutations and developing analysis methods for detecting it from genomic data and high-throughput sequencing. I also have research programs in frequency-dependent selection and scientific computing with Javascript. If you are interested, you can check out my full CV, but I’ve appended a list of recent papers to this post. I can send anyone reprints if desired.

I’m also looking for undergraduate students to join my lab next semester as well. So if you are a current or future ASU undergrad and want to work along side Prof. Steve Steve, send me an email at [Enable javascript to see this email address.].

The application deadline for the graduate program is December 15th, and the process is described here.

Rice University is also looking for a postdoc to fill my vacated Huxley Fellowship. See the ad below the fold.

ASU Graduate Program

Graduate Program in Evolutionary Biology

The Evolutionary Biology PhD program at Arizona State University is recruiting students for entry in the Fall 2012 semester. This new program is interdisciplinary by design and enables faculty and students using diverse models and technologies to engage in novel and innovative research to answer questions related to a number of disciplines including ecology, behavior, physiology, population genetics, bioinformatics, and anthropology.

General information about the program as well as the application process and materials can be found at:

Interested candidates are strongly encouraged to contact listed faculty to inquire about potential openings, fellowships, and general questions about research projects.

Program questions can be directed towards either of the Evolutionary Biology program chairs:

Michael Rosenberg ([Enable javascript to see this email address.])
Brian Verrelli ([Enable javascript to see this email address.])

Cartwright Lab Recent Papers

  1. Cartwright et al (accepted). A family-based probabilistic method for capturing de novo mutations from high-throughput short-read sequencing data. Statistical Applications in Genetics and Molecular Biology.
  2. Conrad et al (2011). Variation in genome-wide mutation rates within and between human families. Nature Genetics, 43:712-714.
  3. Cartwright et al (2011). History can matter: Non-Markovian behavior of ancestral lineages. Systematic Biology, 60:276-290.
  4. Cartwright and Graur (2011). The multiple personalities of Watson and Crick strands. Biology Direct, 6:7.
  5. Price et al (2011). Neutral evolution of robustness in Drosophila microRNA precursors. Molecular Biology and Evolution, 28:2115-2123.
  6. Lücking et al (2011). PICS-Ord: unlimited coding of ambiguous regions by pairwise identity and cost scores ordination. BMC Bioinformatics, 12:10.
  7. Cartwright (2011). Bards, poets, and cliques: Frequency-dependent selection and the evolution of language genes. Bulletin of Mathematical Biology. 73:2201-2212
  8. The 1000 Genomes Project Consortium (2010). A map of human genome variation from population-scale sequencing. Nature, 467:1061-1073.

ASU Genomics Job

Faculty Position in Genomics at Arizona State University

The School of Life Sciences and The Biodesign Institute at Arizona State University invite applications for a tenure-track faculty position at the level of Assistant Professor whose research is at the interface between Genomics and Life Sciences. Research methods may include theoretical, computational, and empirical approaches in population genetics, functional and comparative genomics, and bioinformatics. The successful candidate will be expected to develop an innovative, extramurally-funded, research program, teach at the undergraduate and graduate levels, and have a commitment to outreach and service. The successful candidate will be expected to mentor undergraduate and graduate students as well as postdoctoral fellows. A competitive start-up package and teaching load compatible with high research productivity will be provided.

Arizona State University has made a commitment to accelerating the translation of basic discoveries into practical benefits for society through the construction of state-of-the-art research facilities and the recruitment of world-class faculty members. The successful candidate will participate in university-wide health and/or sustainability initiatives supported by core facilities for functional genomics and next generation sequencing, functional proteomics, high throughput cellular screen, bioinformatics, high performance computing, and imaging. More information on genomic research opportunities at the Biodesign Institute and the School of Life Sciences at ASU can be found at

Candidates must have a Ph.D. (or equivalent) in an appropriate field, and a minimum of 2 years of postdoctoral training is preferred. Demonstrated teaching and research excellence is preferred.

To apply, send cover letter, your curriculum vitae, three representative publications, separate statements of future research plans and teaching philosophy and interests, and contact information for three references to be sent to Alan Rawls, Chair, Genomics Faculty Search Committee, School of Life Sciences, PO Box 874501, Tempe, AZ 85287-4501. Electronic applications sent as PDF files to [Enable javascript to see this email address.] are preferred. The initial closing date for receipt of applications is November 11, 2001; applications will be reviewed weekly thereafter until the search is closed. A background check is required for employment. Arizona State University is an equal opportunity/affirmative action employer committed to excellence through diversity. Women and minorities are encouraged to apply. For additional information on this position and the School of Life Sciences, please visit

Huxley Fellowship in Evolution

The Ecology and Evolutionary Biology Department of Rice University ( seeks to fill a Huxley Fellow position in EVOLUTION. The position is a two-year appointment with a third year extension possible, with a start date of July 1st 2012. Our prestigious Huxley Fellow Program aims to recruit outstanding researchers with a PhD and postdoctoral experience, who merge excellence in teaching (25%) and research (75%). The Huxley Fellows receive faculty status, employee benefits, competitive salary, and research funds for independent or collaborative research. Collaborative interests with the existing faculty are a plus and applicants are encouraged to identify a potential faculty host within the EEB department.

An application (curriculum vitae, statement of research interests and statement of teaching) and three letters of recommendation should be submitted via e-mail to Diane Hatton, [Enable javascript to see this email address.]. Please write “Evolution Huxley Fellow Application” in the subject line. Application review will begin immediately.

For further questions and informal inquiries please contact Dr. Nicholas H Putnam, Huxley Fellow Search Committee, [Enable javascript to see this email address.]. Rice University is an Equal Opportunity/Affirmative Action Employer. Women and minorities are encouraged to apply.


Reed, congratulations on the job. When you get there say hi for me to Sudhir Kumar and lots of other folks there, including the head of the Biodesign Institute, who is a former colleague of mine in my department (he was our very own Nobel laureate).

In case anyone wonders why Rice University can grandly name its fellowship the Huxley Fellowship, in fact Julian Huxley had a connection there. In 1914, after three years of a job at Oxford University, he became head of Biology Department at Rice Institute. On his way there, he stopped to visit Thomas Hunt Morgan’s famous fly lab at Columbia University. He was impressed by one of the graduate students there and offered him a job at Rice Institute. This was H. J. Muller. They overlapped for some months at Rice, then Huxley went back to England and into military service, as World War I had broken out. A major part of his legacy at Rice was H. J. Muller’s presence there for several years.

Sounds like a great opportunity for Reed and any of his future students. I now work in industry. It pays better than academia, and there is a shortage of bioinformaticians. I don’t know how long the shortage will last, but we are at the stage of the early biotech companies of the 1980’s that were hiring microbiologists because they couldn’t get molecular biologists. A few months ago we got two terabases of DNA sequence to analyze. It is more sequence than the DOD generated in the previous year. We are not that big of a company and have openings for two post docs in the field of genomics and bioinformatics.

My guess is that if you get a solid understandings of the basics and can write scripts and analyze tons of data that you won’t have any problem finding a decent paying job at the end of your degree.

Genomes are being sequenced for a few thousand dollars, but it takes people that know what they are doing to make sense of all the data. Getting a degree where you become proficient in grinding through tons of data isn’t going to be a waste of your time, and you stand a chance of figuring out some really interesting problems. Understanding the underlying biology is one of the shortages.

Congratulations. Best wishes.

Congratulations, Reid. It sounds like a fabulous place to work. (But someone tell him that ASU is in Phoenix, not Tempe.…)

But someone tell him that ASU is in Phoenix, not Tempe.…

ASU is in Tempe. UA is in Tuscon.

Reed A. Cartwright said:

But someone tell him that ASU is in Phoenix, not Tempe.…

ASU is in Tempe. UA is in Tuscon.

I thought UA was in Tucson. That’s whose big red “A” is on the mountain, isn’t it? [/pedant]

I will be definitely be applying, Reed. Have you read my journal articles?

Btw, I recently had a paper accepted on the subject of computational pop genetics. One of the regulars on this forum helped me out on it, but I won’t say who.

Atheistoclast said: Btw, I recently had a paper accepted on the subject of computational pop genetics.

Congratulations - seriously. Which journal?

One of the regulars on this forum helped me out on it, but I won’t say who.

Robert Byers?

Paul Burnett said: Congratulations - seriously. Which journal?

I am not going to say until I sign the copyright agreement and receive the proof. I am more cautious these days after some Christian and Jewish fundamentalists lobbied the ID journal, Biocomplexity, to retract a separate article due to my “anti-Semitic” remarks over on TalkRat. But this journal is published by Springer-Verlag and is highly respectable. It is, in fact, the oldest journal on genetics in the world.

Are you willing to post the abstract?

Reed A. Cartwright said:

Are you willing to post the abstract?

OK. That is a reasonable request and this is your thread:

Gene duplicates have the inherent property of initially being functionally redundant. This means that they can compensate for the effect of deleterious variation occurring at one or more sister sites. Here, I present data bearing on evolutionary theory that illustrates the manner in which any functional adaptation in duplicate genes is markedly constrained because of the compensatory utility provided by a sustained genetic redundancy. Specifically, a two-locus epistatic model of paralogous genes was simulated to investigate the degree of purifying selection imposed, and whether this would serve to impede any possible biochemical innovation. Three population sizes were considered to see if, as expected, there was a significant difference in any selection for robustness. Interestingly, physical linkage between tandem duplicates was actually found to increase the probability of any neofunctionalization and the efficacy of selection, contrary to what is expected in the case of singleton genes. The results indicate that an evolutionary trade-off often exists between any functional change under either positive or relaxed selection and the need to compensate for failures due to degenerative mutations, thereby guaranteeing the reliability of protein production

Paul Burnett said:

Reed A. Cartwright said:

But someone tell him that ASU is in Phoenix, not Tempe.…

ASU is in Tempe. UA is in Tuscon.

I thought UA was in Tucson. That’s whose big red “A” is on the mountain, isn’t it? [/pedant]

Indeed it is Paul, and it is an annual tradition to have that red “A” repainted at the start of each academic year.

Anyway, congratulations Reed, and maybe there might be some excellent students at UA who might consider making the leap up to Tempe.

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This page contains a single entry by Reed A. Cartwright published on November 6, 2011 9:55 PM.

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